Journal Articles

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Recent Progress in Glucose-Responsive Insulin,  Diabetes, in press, 2024.

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Engineering Cells for Therapy and Diagnosis,  Nature Reviews Bioengineering, in press, 2024.

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Lyophilized Lymph Nodes for Improved Delivery of Chimeric Antigen Receptor T Cells, Nature Materials, 121(11): e2314349121, 2024.

In Situ Formed Depot of Elastin-like Polypeptide-hirudin Fusion Protein for Long-term Antithrombotic Therapy, Proceedings of the National Academy of Sciences U.S.A. (PNAS), in press, 2024.

Coin-sized, Fully Integrated, and Minimally Invasive Continuous Glucose Monitoring System Based on Organic Electrochemical Transistors, Science Advances, 10(16): eadl1856, 2024.

Platelet-Drug Conjugates Engineered via One-step Fusion Approach for Metastatic and Postoperative Cancer Treatment, Angewandte Chemie International Edition, in press, 2024.

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Cryo-shocked Tumor Cells Deliver CRISPR-Cas9 for Lung Cancer Regression by Synthetic Lethality, Science Advances, 10(13): eadk8264, 2024.

Adavosertib-Encapsulated Metal-Organic Frameworks for p53-Mutated Gallbladder Cancer Treatment via Synthetic Lethality, Science Bulletin, 69(9): 1286-1301, 2024.

Tumor Microenvironment Remodeling-mediated Sequential Drug Delivery Potentiates Treatment Efficacy, Advanced Materials, 2312493, 2024.

Fluorinated Lipid Nanoparticles for Enhancing mRNA Delivery Efficiency, ACS Nano, 18(11): 7825-7836, 2024.

Lymph Node-biomimetic Scaffold Boosts CAR-T Therapy Against Solid Tumor, National Science Review, nwae018, 2024.

Inflammation-Responsive Hydrogel Accelerates Diabetic Wound Healing Through Immunoregulation and Enhanced Angiogenesis,  Advanced Healthcare Materials, 2400150, 2024.

Advances and Challenges in Cerebral Organoids Research, Advanced NanoBiomed Research, 2300126, 2024.

Macroencapsulated Bacteria for in vivo Sensing and Therapeutics, Matter, 7(4): 1440-1465, 2024.

Dissolvable Microneedle Patch Enables Local Delivery of Immunomodulatory Microparticles Containing Bifunctional Molecules for Periodontal Tissue Regeneration, Med-X, in press, 2024.

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Biomimetic Design Strategies for Biomedical Applications, Matter, 7(3): 826-854, 2024.

Week-long Norm Glycaemia in Diabetic Mice and Minipigs via A Subcutaneous Dose of A Glucose-responsive Insulin Complex, Nature Biomedical Engineering, in press, 2023.

Stretchable Graphene Hydrogel Interfaces for Wearable and Implantable Bioelectronics, Nature Electronics, 7(1): 51-65, 2024.

An In Situ Dual-anchoring Strategy for Enhanced Immobilization of PD-L1 to Treat Autoimmune Diseases, Nature Communications, 14(1): 6953, 2023.

Synthesizing Biomaterials in Living Organisms, Chemical Society Reviews, 52(23): 8126-8164, 2023.

Unveiling New Anti-inflammatory Mechanisms of Nanomaterials, National Science Review, 10(12): nwad264, 2023.

Scarless Wound Healing Programmed by Core-shell Microneedles, Nature Communications, 14(1): 3431, 2023.

Microneedles Biomedical Devices, Nature Reviews Bioengineering, 1-19, 2023.

Rationally Designed Approaches to Augment CAR-T Therapy for Solid Tumor Treatment, Bioactive Materials, 33: 377-395, 2024.

TBA, Nature Biomedical Engineering, in press, 2023.

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Activating Tumor-selective Liquid Metal Nanomedicine through Galvanic Replacement, Advanced Materials, 2307817, 2023.

Theranostic Gastrointestinal Residence Systems, Device, 1(2), 2023.

Pre-activated Nanoparticles with Persistent Luminescence for Deep Tumor Photodynamic Therapy in Gallbladder Cancer, Nature Communications, 14, 5699, 2023.

Potentiating Cancer Vaccination by Adjuvant-loaded Cryo-shocked Tumor Cells, Biomaterials, 122319, 2023.

Microneedle-Mediated Cell Therapy, Advanced Science, 2304124, 2023.

Injectable nanosized formulation for glucose-responsive insulin delivery, Nano Today, 51: 101937, 2023.

Ultrarapid-Acting Microneedles for Immediate Delivery of Biotherapeutics, Advanced Materials, 2304582, 2023.

T Cell-Mimicking Platelet-Drug Conjugates, Matter,6(7), 2340, 2023.

Glucose-Responsive Charge-Switchable Lipid Nanoparticles for Insulin Delivery, Angewandte Chemie International Edition, 135(20): e202303097, 2023.

Artificial Intelligence in Pharmaceutical Sciences, Engineering,in press, 2023.

Langmuir−Blodgett-mediated formation of antibacterial microneedles for long-term transdermal drug delivery, Advanced Materials, 2303388, 2023.

Blue-Ringed Octopus Inspired Microneedle Patch for Robust Tissue Surface Adhesion and Active-injection Drug Delivery, Science Advances, 9(25): eadh2213, 2023.

Adoptive Treg Therapy with Metabolic Intervention Ameliorated Psoriasis Syndrome by Perforated Microneedles, Science Advances, 9, eadg6007, 2023.

Advanced Biomaterials Research in China, Advanced Healthcare Materials,12(16): 2301336, 2023.

Inhibition of tumor metastasis by liquid nitrogen-shocked tumor cells with oncolytic viruses infection, Advanced Materials, 2212210, 2023.

Local Drug Delivery Techniques for Triggering Immunogenic Cell Death, Small Methods, 2300347, 2023.

Induction of Tumor Ferroptosis-Dependent Immunity using an Injectable Attractive Pickering Emulsion Gel, Advanced Materials, 2303542, 2023.

Glucose-Responsive Microneedle Patch for Closed-Loop Dual-Hormone Delivery in Mice and Pigs, Science Advances, 8(48): eadd3197, 2022.

Unmanned Aerial Vehicle-Mediated Drug Delivery for First Aid, Advanced Materials, 2208648, 2022.

Localized Nuclear Reaction Breaks Boron Drug Capsules Loaded with Immune Adjuvants for Cancer Immunotherapy, Nature Communications,14, 1884, 2023.

Site-Selective Superassembly of Biomimetic Nanorobots Enabling Deep Penetration into Tumor with Stiff Stroma, Nature Communications, 14(1): 4628, 2023.

Non-invasive Activation of Intratumoural Gene Editing for Improved Adoptive T-cell Therapy in Solid Tumours, Nature Nanotechnology, 18, 933-944, 2023.

Material Design for Oral Insulin Delivery, Med-X,1, 7, 2023.

DNA/DMXAA/metal-organic Framework Activator of Innate Immunity for Boosting Anticancer Immunity, Advanced Materials, 2210440, 2023.

In Situ Interfacial Super-Assembly of Nanobiohybrids through Plant for Food-Grade Oral Medicine, ACS Applied Materials & Interfaces, 15, 5, 7282-7293, 2023.

Metabolic Reprogramming of Nk Cells by Black Phosphorus Quantum Dots Potentiates Cancer Immunotherapy, Advanced Science, 2202519, 2023.

Engineering SIRPα Cellular Membrane-based Nanovesicles for Combination Immunotherapy, Nano Research, 1-9, 2023.

Tissue Engineering in Neuroscience: Applications and Perspectives, BME Frontiers, 4: 0007, 2023.

Bioresponsive Immunotherapeutic Materials, Advanced Materials, 2209778, 2023.

Natural Mussel Protein-derived Antitumor Nanomedicine with Tumor-Targeted Bioadhesion and Penetration, Nano Today, 48: 101700, 2023.

Recent Advances in Oral and Transdermal Protein Delivery Systems, Angewandte Chemie International Edition, 62(10): e202214795, 2023.

Adipocytes Encapsulating Telratolimod Recruit and Polarize Tumor-associated Macrophages for Cancer Immunotherapy, Advanced Science, 2206001, 2022.

Cell Delivery Devices for Cancer Immunotherapy, Journal of Controlled Release, 353: 875-888, 2023.

Microneedles-based Transdermal Detection and Sensing Devices, Lab on a Chip, 23, 869-887, 2023.

Engineered bacteria for augmented in situ tumor vaccinations, Biomaterials Science, 11, 1137-1152, 2023.

Near-Infrared-Ⅱ Fluorescence Imaging for Tumor Diagnosis and Therapy, Chemical Journal of Chinese Universities, 43(12): 20220577, 2022.

Microneedle Patches Loaded with Nanovesicles for Glucose Transporter-mediated Insulin Delivery, ACS Nano, 16, 11, 18223-18231, 2022.

Nanomodulators targeting tumor-resident immunosuppressive cells: mechanisms and recent updates, Nano Today, 47: 101641, 2022.

Pore forming-mediated intracellular protein delivery for enhanced cancer immunotherapy, Science Advances, 8(46): eabq4659, 2022.

Printable personalized drug delivery patch for the topical therapy of skin diseases, Matter, 6(1): 158-174, 2023.

Recent advances of bioresponsive polymeric nanomedicine for cancer therapy, Nano Research, 1-12, 2022.

Engineered T Cell Extracellular Vesicles Displaying PD-1 Boost Anti-tumor Immunity, Nano Today, 46: 101606, 2022.

A Shear-Thinning Biomaterial-Mediated Immune Checkpoint Blockade, ACS Applied Materials & Interfaces, 14, 31, 35309, 2022.

Materials and Carriers Development for Glucose-responsive Insulin, Accounts of Materials Research, 3, 9, 960-970, 2022.

Top-down Shrinking Fabrication of A Glucose-responsive Glucagon Microneedle Patch, Advanced Science, 2203274, 2022.

Advances in Translational 3D Printing for Cartilage, Bone, and Osteochondral Tissue Engineering, Small, 2201869, 2022.

Biomedical polymers: synthesis, properties, and applications, Science China, 65, 1010-1075, 2022.

Microneedle Patch for Day&Night Transdermal Delivery of Growth Hormone, Chinese Journal of Modern Applied Pharmacy, 39(8), 1006-1012, 2022.

Flexible Patch with Printable and Antibacterial Conductive Hydrogel Electrodes for Accelerated Wound Healing, Biomaterials, 285, 121479, 2022.

Soft Patch Interface-Oriented Super-Assembly of Complex Hollow Nanoarchitectures for Dual-Responsive Nanospacecrafts, Journal of the American Chemical Society, 144, 17, 7778-7789, 2022.

Leveraging Biomaterials for Enhancing T Cell Immunotherapy, Journal of Controlled Release, 344, 272-288, 2022.

Convergence of Synthetic Biology and Nanobiotechnology for Biomedical Applications, Synthetic Biology Journal, 2096, 2022.

Advanced Vaccine Delivery, Advanced Drug Delivery Reviews, 183: 114170, 2022.

Cold Atmospheric Plasma Delivery for Biomedical Applications, Materials Today, 54, 153-188, 2022.

Modular Polymer Platform As a Novel Approach to Head and Neck Cancer Therapy, Scientific Reports, 12, 3592, 2022.

Leveraging Macrophages for Cancer Theranostics, Advanced Drug Delivery Reviews, 114136, 2022.

Delivery Strategies in Treatments of Leukemia, Chemical Society Reviews, 51, 2121-2144, 2022.

Bortezomib-Encapsulated Dual Responsive Copolymeric Nanoparticles for Gallbladder Cancer Targeted Therapy, Advanced Science, 2103895, 2022.

Bioorthogonal Catalysis for Biomedical Applications, Trends in Chemistry, 4 (157), 2022.

Smart oral insulin therapy, Matter, 4(3790), 2021.

Tailoring the physicochemical properties of nanomaterials for immunomodulation, Advanced Drug Delivery Reviews, 180 (114039), 2021.

Anti-pneumonia natural tea nanodots, Matter, 4(3083), 2021

Cellular Transformers for Targeted Therapy, Advanced Drug Delivery Reviews, 179 (114032), 2021

Macroencapsulation Devices for Cell Therapy, Engineering, in press, 2021

Treating diabetes with "cookies", Nature Chemical Biology, 18 (3), 2022

Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy, National Science Review, nwab172, 2021

ZnS@BSA Nanoclusters Potentiate Efficacy of Cancer Immunotherapy, Advanced Materials, 33, 2104037, 2021

Microneedle-Mediated Therapy for Cardiovascular Diseases, Drug Delivery and Translational Research, 12, 472-483, 2022

Fibrin Gel Enhances the Antitumor Effects of Chimeric Antigen Receptor T Cells in Glioblastoma, Science Advances, 7(eabg5841), 2021

Engineered platelets: advocates for tumor immunotherapy, Nano Today, 40(101281), 2021

Recent Advances in Transdermal Sensors for Glucose Monitoring, Current Opinion in Biomedical Engineering, 20(100326), 2021

Microneedle-Mediated Vaccination: Innovation and Translation, Advanced Drug Delivery Reviews, 179, 113919, 2021

Iron oxide nanoparticles augment the intercellular mitochondrial transfer mediated therapy, Science Advances, 7(eabj0534), 2021

From Mouse to Mouse-Ear Cress: Nanomaterials as Vehicles in Plant Biotechnology, Exploration, 1(9), 2021

Strategies for Browning Agent Delivery, Pharmaceutical Research, 38(1327), 2021

Portable air-fed cold atmospheric plasma device for post-surgical cancer treatment, Science Advances, 7(eabg5686), 2021

Infectious Diseases as a Global Threat – Challenges and Opportunities for Drug Delivery Science, Drug Delivery and Translational Research, 11(1316), 2021

Integrated Microneedle-Smartphone Nucleic Acid Amplification Platform for In-Field Diagnosis of Plant Diseases, Biosensors and Bioelectronics, 187(113312), 2021

Bioorthogonal catalytic patch, Nature Nanotechnology, 16(933), 2021

Adipocyte-Derived Anticancer Lipid Droplet, Advanced Materials, 2021, 33, 2100629

Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis, Nature Communications, 12(2773), 2021

Stimuli-responsive transdermal microneedle patches for drug delivery, Materials Today, 47(206), 2021

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets, Nature Biomedical Engineering, 5(1038), 2021

Injectable Biodegradable Polymeric Complex for Glucose-Responsive Insulin Delivery, ACS Nano, 15(4294), 2021

Nanodevices for cancer vaccination, Nature Materials, 20(286), 2021

Delivery Techniques for Enhancing CAR T-Cell Therapy against Solid Tumors, Advanced Functional Materials, 31(2009489), 2021

Topographical nanostructures for physical sterilization, Drug Delivery and Translational Research, 11, (1376), 2021

Cancer-on-a-chip for modeling immune checkpoint inhibitor and tumor interactions, Small, 17(2004282), 2021

Microneedle array patches integrated with nanoparticles for therapy and diagnosis, Small Structures, 4(2000097), 2021

Cryo-shocked cancer cells for targeted drug delivery and vaccination, Science Advances, 6(eabc3013), 2020

Microneedle-array patch with pH-sensitive formulation for glucose-responsive insulin delivery, Nano Research, 14 (2689), 2021

Developing Insulin Delivery Devices with Glucose-Responsiveness, Trends in Pharmacological Sciences, 1 (31), 2021

Cyborg Vessel, Matter, 5(1393), 2020

Dual self-regulated delivery of insulin and glucagon by a hybrid patch, Proceedings of the National Academy of Sciences U.S.A. (PNAS), 117(29512), 2020

Colloidal crystal microneedle patch for glucose monitoring, Nano Today, 35(100984), 2020

Tailoring Materials for Modulation of Macrophage Fate, Advanced Materials, 12(2004172), 2021

Engineering Antiviral Vaccines, ACS Nano, 10(12370), 2020

Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics, Accounts of Chemical Research, 11(2521), 2020

Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy, Proceedings of the National Academy of Sciences U.S.A. (PNAS), 7(3687), 2020

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs, Nature Biomedical Engineering, 4(499), 2020 (Cover Feature)

Unraveling the Mechanobiology of Immune Cells, Current Opinion in Biotechnology, 66(236), 2020

Biodegradable Microneedle Patch for Transdermal Gene Delivery, Nanoscale, 12(16724), 2020

Therapeutic Potential of Adipose Tissue, Science Bulletin, 20(1702), 2020

Advances in antimicrobial microneedle patches for combating infections, Advanced Materials, 33(2002129), 2020

Calming Cytokine Storm in Pneumonia by Targeted Delivery of TPCA-1 Using Platelet-Derived Extracellular Vesicles, Matter, 3(1), 2020

Targeted Delivery of Notch Inhibitor Attenuates Obesity-induced Glucose Intolerance and Liver Fibrosis, ACS Nano, 6(6878), 2020

Transdermal drug delivery for hair regrowth, Molecular Pharmaceutics, 2(483), 2020

Toward nanoscopic cellular imaging by X-ray, National Science Review, nwaa206, 2020 (Research Highlights)

PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes, Advanced Materials, 26(1907692), 2020

Biodegradable beta-cyclodextrin conjugated gelatin methacryloyl microneedle for delivery of water-insoluble drug, Advanced Healthcare Materials, 11(2000527), 2020

CRISPR-Cas12a delivery by DNA-mediated bio-responsive editing for cholesterol regulation, Science Advances, 21(eaba2983), 2020

Advances in Engineering Local Drug Delivery Systems for Cancer Immunotherapy, WIREs Nanomedicine & Nanobiotechnology, 5(e1632), 2020

Transdermal Colorimetric Patch for Hyperglycemia Sensing in Diabetic Mice, Biomaterials, 237(119782), 2020

Cargo-Encapsulated Cells for Drug Delivery, Science China Life Sciences, 63(599), 2020

DNA Extraction from Plant Leaves Using a Microneedle Patch, Current Protocols in Plant Biology, 1(e20104), 2020

Gelatin methacryloyl microneedle patches for minimally-invasive extraction of skin interstitial fluid, Small, 16(1905910), 2020

Engineering Biomaterials with Micro/Nano Technologies for Cell Reprogramming, ACS Nano, 14(1296), 2020

Progress in Transdermal Drug Delivery Systems for Cancer Therapy, Nano Research, 13(1810), 2020

Nanotechnology against Diabetes, Nanotechnology, 32(1), 2020

Non-transdermal Microneedles for Advanced Drug Delivery, Advanced Drug Delivery Reviews, 165(41), 2020

Rational designs of in vivo CRISPR-Cas delivery systems, Advanced Drug Delivery Reviews, 168 (3), 2020

A prophylactic and a therapeutic against AML, Nature Biomedical Engineering, 4(4), 2020

Engineering Glucose-Responsive Insulin, Medicine in Drug Discovery, 3(100010), 2019

Advances in nanomedicine for cancer starvation therapy, Theranostics, 26(8026), 2019

Adipocytes as Anticancer Drug Delivery Depot, Matter, 5(1203), 2019

Combretastatin A4 nanodrug-induced MMP9-amplification boosts tumor-selective release doxorubicin prodrug, Advanced Materials, 44(1904278), 2019

A Forskolin-Conjugated Insulin Analog Targeting Endogenous Glucose-Transporter for Glucose-Responsive Insulin Delivery, Biomaterials Science, 7(4508), 2019

Advances in Engineering Cells for Cancer Immunotherapy, Theranostics, 25(7889), 2019

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs, Science Advances, 5(eaaw4357), 2019

Glucose Transporter Inhibitor-Conjugated Insulin Mitigates Hypoglycemia, Proceedings of the National Academy of Sciences U.S.A. (PNAS), 22(10744), 2019

Application of nanotechnology in cancers prevention, diagnose and treatment, Science and Technology Review, 22(96), 2018

Sprayable Gel for Post-surgical Immunotherapy, Immuno-Oncology Technology, 2(11), 2019

Sequentially Site-Specific Delivery of Thrombolytic and Neuroprotectant for Enhanced Treatment of Ischemic Stroke Based on Bioengineered Nanoplatelet, ACS Nano, 8(8577), 2019

Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy, Nano Letters, 8(4879), 2019

On the issue of transparency and reproducibility in nanomedicine, Nature Nanotechnology, 14(629), 2019

Eradication of unresectable liver metastasis through induction of tumour specific energy depletion, Nature Communications, 10(3051), 2019

In situ fabrication of organic electrochemical transistors on a microfluidic chip, Nano Research, 8(1943), 2019

Nanoscience and Nanotechnology at UCLA, ACS Nano, 13(6127), 2019

Glucose-responsive insulin and delivery systems: innovation and translation, Advanced Materials, 13(1902004), 2020

Red Blood Cell Derived Nanoerythrosome for Antigen Delivery with Enhanced Cancer Immunotherapy, Science Advances, 10(eaaw6870), 2019

Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases, ACS Nano, 6(6540), 2019

Tailoring Biomaterials for Metabolic Diseases, Advanced Healthcare Materials, 12(1900632), 2019 (Editorial)

Polybrominated diphenyl ethers perturb axonal growth and actin distribution, BIBECHANA, 16(64), 2019

Enzyme-Activatable Polymer-Drug Conjugate Augments Tumour Penetration and Treatment Efficacy, Nature Nanotechnology, 14(799), 2019

Advances in Drug Delivery for Post-Surgical Cancer Treatment, Biomaterials, 219(119182), 2019

Advances of Injectable Hydrogel-based Scaffolds for Cartilage Regeneration, Regenerative Biomaterials, 2(129), 2019

Bioinspired and Biomimetic Nanomedicines, Accounts of Chemical Research, 5(1255), 2019

A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth, ACS Nano, 4(4354), 2019

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells, Advanced Materials, 23(1900192), 2019

A Dual-Bioresponsive Drug Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade, Advanced Materials, 17(1806957), 2019

Engineering Protein Delivery Depots for Cancer Immunotherapy, Bioconjugate Chemistry, 3(515), 2019

Enhanced local cancer therapy by CA4P and CDDP co-loaded polypeptide gel depot, Biomaterials Science, 7(860), 2019

Cancer Stem Cell-Platelet Hybrid Membrane-Coated Magnetic Nanoparticles for Enhanced Photothermal Therapy of Head and Neck Squamous Cell Carcinoma, Advanced Functional Materials, 10(1807733), 2019

Advances in Transdermal Insulin Delivery, Advanced Drug Delivery Reviews, 139(51), 2019

Glucose-responsive oral insulin delivery for postprandial glycemic regulation, Nano Research, 7(1539), 2019

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment, Nature Nanotechnology, 14(89), 2019 (Cover Feature)

Shape-Controlled Synthesis of Liquid Metal Nanodroplets for Photothermal Therapy, Nano Research, 3(1313), 2019

Biodegradable Gelatin Methacryloyl Microneedles for Transdermal Drug Delivery, Advanced Healthcare Materials, 3(1801054), 2019

Strategies of combination drug delivery for immune checkpoint blockade, Advanced Healthcare Materials, 4(1801099), 2019

Cardiac cell-integrated microneedle patch for treating myocardial infarction, Science Advances, 11(eaat9365), 2018

Platelet for Drug Delivery, Current Opinion in Biotechnology, 58(81), 2019

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy, Nature Biomedical Engineering, 2(831), 2018

Local generation of hydrogen for enhanced photothermal therapy, Nature Communications, 9(4241), 2018

The Inaugural Nano Research Young Innovators (NR45) Award in Nanobiotechnology, Nano Research, 10(4931), 2018 (Editorial)

Cationic lipid-assisted nanoparticles for delivery of mRNA cancer vaccine, Biomaterials Science, 11(3009), 2018

Blood sampling using microneedles as a minimally invasive platform for biomedical diagnostics, Applied Materials Today, 13(144), 2018

Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases, Nature Communications, 9(4092), 2018

Engineering PD-1-Presenting Platelets for Cancer Immunotherapy, Nano Letters, 9(5716), 2018

Delivery Strategy for Immune Checkpoint Blockade, Advanced Healthcare Materials, 20(1800424), 2018

In Situ Formed Reactive Oxygen Species-Responsive Scaffold with Gemcitabine and Checkpoint Inhibitor for Combination Therapy, Science Translational Medicine, 429(eaan3682), 2018

Leveraging Engineering of Cells for Drug Delivery, Accounts of Chemical Research, 3(668), 2018

Advances in Liquid Metals for Biomedical Applications, Chemical Society Reviews, 8(2518), 2018

Towards Enhancing Skin Drug Delivery, Advanced Drug Delivery Reviews, 127(1), 2018

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade, Advanced Materials, 28(1801527), 2018

The Potential of a Microneedle Patch for Reducing Obesity, Expert Opinion on Drug Delivery, 5(431), 2018

Glucose-Responsive Microneedle Patches for Diabetes Treatment, Journal of Diabetes Science and Technology, 1(41), 2019

PD‐1 Blockade Cellular Vesicles for Cancer Immunotherapy, Advanced Materials, 22(1707112), 2018

Advances in Transformable Drug Delivery Systems, Biomaterials, 178(546), 2018

Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy, ACS Nano, 6(5995), 2018

Punching and Electroporation for Enhanced Transdermal Drug Delivery, Theranostics , 13 (3688), 2018

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery, Small, 14(1704181), 2018

ROS‐Responsive Microneedle Patch for Acne Vulgaris Treatment, Advanced Therapeutics, 3(1800035), 2018

Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment, Nano Letters, 4(2294), 2018

Nanomedicine for Obesity Treatment, Science China Life Sciences, 4(373), 2018

Advances in Glycosylation-Mediated Cancer-Targeted Drug Delivery, Drug Discovery Today, 5(1126), 2018

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery, ACS Nano, 3(2466), 2018

Synthetic beta cells for fusion-mediated dynamic insulin secretion, Nature Chemical Biology, 14(86), 2018

Polymeric Microneedles for Transdermal Protein Delivery, Advanced Drug Delivery Reviews, 127(106), 2018

Advances in Bioresponsive Closed-loop Drug Delivery Systems, International Journal of Pharmaceutics, 2(350), 2018

Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles, ACS Nano, 2(994), 2018

Cellular Bioparticulates with Therapeutics for Cancer Immunotherapy, Bioconjugate Chemistry, 3(702), 2018

Targeted repair of heart injury by stem cells fused with platelet nanovesicles, Nature Biomedical Engineering, 2(17), 2018

Injectable Thermo-Sensitive Polypeptide-based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy, Biomacromolecules,12(4341), 2018

Red Blood Cells for Drug Delivery, Small Methods, 12(1700270), 2017

Cysteine-rich Proteins for Drug Delivery and Diagnosis, Current Medicinal Chemistry, 24, 2017

KO of 5-InsP7 kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype, Proceedings of the National Academy of Sciences U.S.A. (PNAS), 114(11968), 2017

A Melanin-Mediated Cancer Immunotherapy Patch, Science Immunology, 2(eaan5692), 2017

Glucose responsive insulin by molecular and physical design, Nature Chemistry, 9(937), 2017

Locally-Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment, ACS Nano, 11(9223), 2017

Kidney Physiology: A Size Bandpass Filter, Nature Nanotechnology, 12, 2017

Bioresponsive Transcutaneous Patches, Current Opinion in Biotechnology, 48(28), 2017

Leveraging H2O2 Levels for Biomedical Applications, Advanced Biosystems, 1(9), 2017

Insulin-Responsive Glucagon Delivery for Prevention of Hypoglycemia, Small, 13(19), 2017

Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs, Theranostics, 7(3504), 2017

Enhanced Endosomal Escape by Light-fueled Liquid-metal Transformer, Nano Letters, 17(2138), 2017

Stimuli-Responsive Polymersomes for Biomedical Applications, Biomacromolecules, 18(649), 2017

Red Blood Cells for Glucose-Responsive Insulin Delivery, Advanced Materials, 29(18), 2017

Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook, Advanced Materials, 29 (1606036), 2017

Photoacoustic Drug Delivery, Sensors, 17, 2017

In situ Activation of Platelets with Checkpoint Inhibitors for Post-Surgical Cancer Immunotherapy, Nature Biomedical Engineering, 0011, 2017

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery, Nano Letters, 17(733), 2017

Conjugated Polymer Nanomaterials for Theranostics, Acta Pharmacologica Sinica, 38, 2017

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy, Advanced Materials, 29(1605803), 2017

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species, Nano Letters, 17(928), 2017

Ultrasound-Triggered Noninvasive Regulation of Blood Glucose Levels Using Microgels Integrated with Insulin Nanocapsules, Nano Research, 10(1393), 2017

Anaerobe-inspired anticancer nanovesicles, Angewandte Chemie International Edition, 10(2588), 2017

Tailoring Non-Viral Delivery Vehicles for Transporting Genome-Editing Tools, Science China Materials, 60(6), 2017

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery, ACS Nano,11(613), 2017

Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation, Advanced Materials, 29(1604043), 2017

Investigation and Intervention of Autophagy to Guide Cancer Treatment with Nanogels, Nanoscale, 9(150), 2017

Engineering Platelet-Mimicking Drug Delivery Vehicles, Frontiers of Chemical Science and Engineering,1, 2017

Bioresponsive Materials, Nature Reviews Materials, 1(16075), 2016

Introduction to special issue-Responsive Materials and Systems: Toward Smart and Precision Medications, Bioengineering and Translational Medicine, 1(235). 2016

Mechanical Force-Triggered Drug Delivery, Chemical Reviews, 116(12536), 2016

Synergistic transcutaneous immunotherapy enhances antitumor immune responses through delivery of checkpoint inhibitors, ACS Nano, 10(8956), 2016

Stimuli-Responsive Delivery of Therapeutics for Diabetes Treatment, Bioengineering and Translational Medicine, 1(323), 2016

Local Delivery of Checkpoints Antibodies, Human Vaccines & Immunotherapeutics, 13(245), 2016

Engineered Nano-platelets for Enhanced Treatment of Multiple Myeloma and Thrombus, Advanced Materials, 28(9573), 2016

Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles, Molecular Pharmaceutics, 13(3506), 2016

Dual Targeted Nanocarrier for Brain Ischemic Stroke Treatment, Journal of Controlled Release, 233(64), 2016

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody, Nano Letters, 16(2334), 2016

Transformable DNA Nanocarriers for Plasma Membrane Targeted Delivery of Cytokines, Biomaterials, 96(1), 2016

Internalized Compartments Encapsulated Nanogels for Targeted Drug Delivery, Nanoscale, 8(9178), 2016

ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging, Theranostics, 6(1053), 2016

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy, Advanced Materials, 28(3313), 2016

Hypoxia-Sensitive Materials for Biomedical Applications, Annals of Biomedical Engineering, 44(1931), 2016

Leveraging Physiology for Precision Drug Delivery, Physiological Reviews, 97(189), 2017

Microneedles Integrated with Pancreatic Cells and Synthetic Glucose‐Signal Amplifiers for Smart Insulin Delivery, Advanced Materials, 28(3115), 2016

Tumor Microenvironment and Intracellular Signal-Activated Nanomaterials for Anticancer Drug Delivery, Materials Today, 19(274), 2016

Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots, Nano Letters, 16(1118), 2016

Inflammation‐Triggered Cancer Immunotherapy by Programmed Delivery, Advanced Materials, 28(8912), 2016

Photo-Crosslinked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration, ACS Nano, 10(1292), 2016

Elastic Drug Delivery: could treatments be triggered by patient movement?, Nanomedicine, 11(323), 2016

ATP-Responsive Drug Delivery Systems, Expert Opinion on Drug Delivery, 13(311), 2016

Transformable Liquid-Metal Nanomedicine, Nature Communications, 6(10066), 2015

Microneedle-Array Patches Loaded with Hypoxia-Sensitive Vesicles Provide Fast Glucose-Responsive Insulin Delivery, Proceedings of the National Academy of Sciences U.S.A. (PNAS), 112(8260), 2015

Recent Advances in Cocktail chemotherapy by Combination Drug Delivery Systems, Advanced Drug Delivery Reviews, 98(19), 2015

Anticancer Platelet-Mimicking Nanovehicles, Advanced Materials, 27(7043), 2015

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing, Angewandte Chemie International Edition, 127(12197), 2015

Versatile Protein Nanogels Prepared by In Situ Polymerization, Macromolecular Chemistry and Physics, 217(333), 2015

Stretch-Triggered Drug Delivery from Wearable Elastomer Containing Therapeutic Depots, ACS Nano, 9(9407), 2015

Polypyrrole-Based Implantable Electroactive Pump for Controlled Drug Microinjection, ACS Applied Materials & Interfaces, 7(14563), 2015

Accelerating the Translation of Nanomaterials in Biomedicine, ACS Nano, 9(6644), 2015

Spatiotemporal Drug Delivery Using Laser-Generated-Focused Ultrasound System, Journal of Controlled Release, 220(592), 2015

Confinement-Induced Nanocrystal Alignment of Conjugated Polymer by the Soft-Stamped Nanoimprint Lithography, Chinese Physics B, 24(10), 2015

Rolling Circle Replication for Engineering Drug Delivery Carriers, Editorial for Therapeutic Delivery, 6(765), 2015

Engineering Synthetic Insulin-Secreting Cells Using Hyaluronic Acid Microgels Integrated with Glucose-Responsive Nanoparticles, Cellular and Molecular Bioengineering, 8(445), 2015

Dual Wavelength-Activatable Gold Nanorods Complex for Synergistic Cancer Treatment, Nanoscale, 7(12096), 2015

Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesis, Scientific Reports, 5(9341), 2015

Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene, Advanced Materials, 27(1021), 2015

Programmable Nanomedicine: Synergistic and Sequential Drug Delivery Systems, Nanoscale, 7(3381), 2015

ATP-Responsive DNA-Graphene Hybrid Nanoaggregates for Anticancer Drug Delivery, Biomaterials, 50(67), 2015

Glucose-Responsive Synthetic Closed-Loop Insulin Delivery Systems, Progress in Chemistry, 1(11), 2015

Engineering DNA-Scaffolds for Delivery of Anticancer Therapeutics, Biomaterials Science, 3(1018), 2015

Recent advances in nanotechnology for diabetes treatment, WIREs Nanomedicine & Nanobiotechnology, 7(548), 2015

Cocoon-like Self-Degradable DNA-Nanoclew for Anticancer Drug Delivery, Journal of the American Chemical Society, 136(14722), 2014

Bio-Inspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin, Biomacromolecules, 15(3495), 2014

Emerging Micro- and Nanotechnology Based Synthetic Approaches for Insulin Delivery, Chemical Society Reviews, 43(3595), 2014

Self-Folded Redox/pH Dual-Responsive Nanocarriers for Anticancer Drug Delivery, Chemical Communications, 50(15105), 2014

Clickable Protein Nanocapsules for Targeted Delivery of Recombinant p53 Protein, Journal of the American Chemical Society, 136(15309), 2014

Enzyme-Responsive Nanomaterials for Controlled Drug Delivery, Nanoscale, 6(12273), 2014

Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery, Angewandte Chemie International Edition, 53(5810), 2014

ATP-Triggered Anticancer Drug Delivery, Nature Communications, 5, 3364, 2014.

Stimuli-Responsive Nanomaterials for Therapeutic Protein Delivery, Journal of Controlled Release, 194(1), 2014

Folding Graft Copolymer with Pendant Drug Segment for Co-Delivery of Anticancer Drugs, Biomaterials, 35(7194), 2014

A Temperature Microsensor for Measuring Laser-Induced Heating in Gold Nanorods, Analytical & Bioanalytical Chemistry, 407(719), 2015

Advances in Anticancer Protein Delivery using Micro-/Nanoparticles, Particle, 31(1204), 2014

pH-Responsive and Near-Infrared-Emissive Polymer Nanoparticles for Simultaneous Delivery, Release, and Fluorescence Tracking of Doxorubicin in vivo, Chemical Communications, 50(4699), 2014

Recent Progress in Multi-Drug Delivery to Cancer Cells by Liposomes, Nanomedicine, 9(1117), 2014

Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo, Advanced Healthcare Materials, 3(1392), 2014

Hybrid Fe3O4-Poly (Acrylic Acid) Nanogels for Theranostic Cancer Treatment, Journal of Biomedical Nanotechnology, 11(771), 2014

Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy, Advanced Functional Materials, 24(2295), 2014

Ultrasound-Triggered Regulation of Blood Glucose Levels Using Nano-Network, Advanced Healthcare Materials, 3(811), 2014

Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery, ACS Nano, 7(6758), 2013

Lipid-Modified Aminoglycoside Derivatives for in vivo siRNA Delivery, Advanced Materials, 25(4641), 2013

Hybrid Hydroxyapatite Nanoparticle Colloidal Gels are Injectable Fillers for Bone Tissue Engineering, Tissue Engineering, 19(2586), 2013

Injectable Nano-Network for Glucose-Mediated Insulin Delivery, ACS Nano, 7(4194), 2013

Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug, Biomaterials, 34(5792), 2013

Degradable Polymeric Nanocapsule for Efficient Intracellular Delivery of a High Molecular Weight Tumor-Selective Protein Complex, Nano Today, 8(11), 2013

Tailoring Nanocarriers for Intracellular Protein Delivery, Chemical Society Reviews, 40(3638), 2011

Redox-Responsive Nanocapsules for Intracellular Protein Delivery, Biomaterials, 32(5223), 2011

Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus-Quantum Dot Conjugates, ACS Nano, 5(3523), 2011

Detection of Mercury Ion by Infrared Fluorescent Protein and Its Hydrogel-Based Paper Assay, Analytical Chemistry, 83(2324), 2011

Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules, ACS Nano, 5 (1385), 2011

Conjugated Polymer Fluorescence Probe for Intracellular Imaging of Magnetic Nanoparticles, Macromolecules, 43 (10348), 2010

Probing Protease Activity by Single-Fluorescent-Protein Nanocapsules, Chemical Communications, 46 (6467), 2010

Enzyme-Assisted Photolithography for Spatial Functionalization of Hydrogels, Lab on a Chip, 10 (1946), 2010

Hybrid Nanocomposites of Semiconductor Nanoparticles and Conjugated Polyelectrolytes and Their Application as Fluorescence Biosensors, Polymer, 51 (902), 2010

A Novel Intracellular Protein Delivery Platform Based on Single-Protein Nanocapsules, Nature Nanotechnology, 5(48), 2010

Protein Nanocapsule Weaved with Enzymatically Degradable Polymeric Network, Nano Letters, 12(4533), 2009

Biomolecular Nanopatterning by Magnetic Electric Lithography, Angewandte Chemie International Edition, 48(952), 2009

A CMOS Microarray with On-chip Decoder/Amplifier and Its Integration with Bio-Nano-System, Journal of Semiconductors, 29(1947), 2008

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An Organic/Si Nanowire Hybrid Field Configurable Transistor, Nano Letters, 3(876), 2008

Anionic Water-Soluble Poly(phenylenevinylene) Alternating Copolymer:? High-Efficiency Photoluminescence and Dual Electroluminescence, Macromolecules, 39 (3125), 2006

Dual Electroluminescence from a Single-Component Light-emitting Electrochemical Cell Based on Water-Soluble Conjugated Polymer, Journal of Applied Polymer Science, 100(2930), 2006